Drugs Being Eliminated via the Same Pathway Will Not Always Require Similar Pediatric Dose Adjustments

For scaling drug plasma clearance (CLp) from adults to children, extrapolations of population pharmacokinetic (PopPK) covariate models between drugs sharing an elimination pathway have enabled accelerated development of pediatric models and dosing recommendations. This study aims at identifying cond...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:CPT Pharmacometrics Syst Pharmacol
Main Authors: Calvier, Elisa A. M., Krekels, Elke H. J., Yu, Huixin, Välitalo, Pyry A. J., Johnson, Trevor N., Rostami‐Hodjegan, Amin, Tibboel, Dick, van der Graaf, Piet H., Danhof, Meindert, Knibbe, Catherijne A. J.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5869561/
https://ncbi.nlm.nih.gov/pubmed/29399979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12273
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados