Caged circular siRNAs for photomodulation of gene expression in cells and mice

By means of RNA interference (RNAi), small interfering RNAs (siRNAs) play important roles in gene function study and drug development. Recently, photolabile siRNAs were developed to elucidate the process of gene silencing in terms of space, time and degree through chemical modification of siRNAs. We...

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Bibliografiske detaljer
Udgivet i:Chem Sci
Main Authors: Zhang, Liangliang, Liang, Duanwei, Wang, Yuan, Li, Dong, Zhang, Jinhao, Wu, Li, Feng, Mengke, Yi, Fan, Xu, Luzheng, Lei, Liandi, Du, Quan, Tang, XinJing
Format: Artigo
Sprog:Inglês
Udgivet: Royal Society of Chemistry 2017
Fag:
Chemistry
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5869302/
https://ncbi.nlm.nih.gov/pubmed/29629072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc03842a
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