Photomodulating RNA cleavage using photolabile circular antisense oligodeoxynucleotides

Caged antisense oligodeoxynucleotides (asODNs) are synthesized by linking two ends of linear oligodeoxynucleotides using a photocleavable linker. Two of them (H30 and H40) have hairpin-like structures which show a large difference in thermal stability (ΔT(m) = 17.5°C and 11.6°C) comparing to uncaged...

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Bibliographic Details
Main Authors: Tang, XinJing, Su, Meng, Yu, LiLi, Lv, Cong, Wang, Jie, Li, ZhongJin
Format: Artigo
Language:Inglês
Published: Oxford University Press 2010
Subjects:
Synthetic Biology and Chemistry
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887953/
https://ncbi.nlm.nih.gov/pubmed/20164090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq079
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