Caged circular siRNAs for photomodulation of gene expression in cells and mice

By means of RNA interference (RNAi), small interfering RNAs (siRNAs) play important roles in gene function study and drug development. Recently, photolabile siRNAs were developed to elucidate the process of gene silencing in terms of space, time and degree through chemical modification of siRNAs. We...

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Опубликовано в: :Chem Sci
Главные авторы: Zhang, Liangliang, Liang, Duanwei, Wang, Yuan, Li, Dong, Zhang, Jinhao, Wu, Li, Feng, Mengke, Yi, Fan, Xu, Luzheng, Lei, Liandi, Du, Quan, Tang, XinJing
Формат: Artigo
Язык:Inglês
Опубликовано: Royal Society of Chemistry 2017
Предметы:
Chemistry
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5869302/
https://ncbi.nlm.nih.gov/pubmed/29629072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc03842a
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