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Caged circular siRNAs for photomodulation of gene expression in cells and mice

By means of RNA interference (RNAi), small interfering RNAs (siRNAs) play important roles in gene function study and drug development. Recently, photolabile siRNAs were developed to elucidate the process of gene silencing in terms of space, time and degree through chemical modification of siRNAs. We...

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Publicado en:Chem Sci
Autores principales: Zhang, Liangliang, Liang, Duanwei, Wang, Yuan, Li, Dong, Zhang, Jinhao, Wu, Li, Feng, Mengke, Yi, Fan, Xu, Luzheng, Lei, Liandi, Du, Quan, Tang, XinJing
Formato: Artigo
Lenguaje:Inglês
Publicado: Royal Society of Chemistry 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5869302/
https://ncbi.nlm.nih.gov/pubmed/29629072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc03842a
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