Caged circular siRNAs for photomodulation of gene expression in cells and mice

By means of RNA interference (RNAi), small interfering RNAs (siRNAs) play important roles in gene function study and drug development. Recently, photolabile siRNAs were developed to elucidate the process of gene silencing in terms of space, time and degree through chemical modification of siRNAs. We...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Chem Sci
Prif Awduron: Zhang, Liangliang, Liang, Duanwei, Wang, Yuan, Li, Dong, Zhang, Jinhao, Wu, Li, Feng, Mengke, Yi, Fan, Xu, Luzheng, Lei, Liandi, Du, Quan, Tang, XinJing
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Royal Society of Chemistry 2017
Pynciau:
Chemistry
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5869302/
https://ncbi.nlm.nih.gov/pubmed/29629072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc03842a
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