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Light-dependent RNA interference with nucleobase-caged siRNAs

Within the past years RNA interference (RNAi) has become one of the most valuable tools for post-transcriptional gene silencing. Making RNAi temporally and/or spatially controllable would even enlarge its scope of application. Attaching a light-removable protection group to siRNAs is a very promisin...

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Détails bibliographiques
Auteurs principaux: Mikat, Vera, Heckel, Alexander
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2080613/
https://ncbi.nlm.nih.gov/pubmed/17951332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.753407
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