Cell-specific RNA interference by peptide-inhibited-peptidase-activated siRNAs

The use of chemically-synthesized short interfering RNAs (siRNAs) is the key method of choice to manipulate gene expression in mammalian cell cultures and in vivo. Several previous studies have aimed at inducing cell-specific RNA interference (RNAi) in order to use siRNA molecules as therapeutic rea...

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Main Authors: Koehn, Sandra, Schaefer, Hendrik W, Ludwig, Mirko, Haag, Natja, Schubert, Ulrich S, Seyfarth, Lydia, Imhof, Diana, Markert, Udo R, Poehlmann, Tobias G
Format: Artigo
Sprog:Inglês
Udgivet: Library Publishing Media 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3043559/
https://ncbi.nlm.nih.gov/pubmed/21350683
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