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RNA interference using boranophosphate siRNAs: structure–activity relationships
In RNA interference (RNAi), short double-stranded RNA (known as siRNA) inhibits expression from homologous genes. Clinical or pre-clinical use of siRNAs is likely to require stabilizing modifications because of the prevalence of intracellular and extracellular nucleases. In order to examine the effe...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC534620/ https://ncbi.nlm.nih.gov/pubmed/15545637 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh936 |
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