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Matching material and cellular timescales maximizes cell spreading on viscoelastic substrates

Recent evidence has shown that, in addition to rigidity, the viscous response of the extracellular matrix (ECM) significantly affects the behavior and function of cells. However, the mechanism behind such mechanosensitivity toward viscoelasticity remains unclear. In this study, we systematically exa...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Gong, Ze, Szczesny, Spencer E., Caliari, Steven R., Charrier, Elisabeth E., Chaudhuri, Ovijit, Cao, Xuan, Lin, Yuan, Mauck, Robert L., Janmey, Paul A., Burdick, Jason A., Shenoy, Vivek B.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866566/
https://ncbi.nlm.nih.gov/pubmed/29507238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1716620115
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