Matching material and cellular timescales maximizes cell spreading on viscoelastic substrates

Recent evidence has shown that, in addition to rigidity, the viscous response of the extracellular matrix (ECM) significantly affects the behavior and function of cells. However, the mechanism behind such mechanosensitivity toward viscoelasticity remains unclear. In this study, we systematically exa...

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Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Gong, Ze, Szczesny, Spencer E., Caliari, Steven R., Charrier, Elisabeth E., Chaudhuri, Ovijit, Cao, Xuan, Lin, Yuan, Mauck, Robert L., Janmey, Paul A., Burdick, Jason A., Shenoy, Vivek B.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2018
Предметы:
PNAS Plus
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866566/
https://ncbi.nlm.nih.gov/pubmed/29507238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1716620115
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