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Matching material and cellular timescales maximizes cell spreading on viscoelastic substrates

Recent evidence has shown that, in addition to rigidity, the viscous response of the extracellular matrix (ECM) significantly affects the behavior and function of cells. However, the mechanism behind such mechanosensitivity toward viscoelasticity remains unclear. In this study, we systematically exa...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Gong, Ze, Szczesny, Spencer E., Caliari, Steven R., Charrier, Elisabeth E., Chaudhuri, Ovijit, Cao, Xuan, Lin, Yuan, Mauck, Robert L., Janmey, Paul A., Burdick, Jason A., Shenoy, Vivek B.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866566/
https://ncbi.nlm.nih.gov/pubmed/29507238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1716620115
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