Matching material and cellular timescales maximizes cell spreading on viscoelastic substrates

Recent evidence has shown that, in addition to rigidity, the viscous response of the extracellular matrix (ECM) significantly affects the behavior and function of cells. However, the mechanism behind such mechanosensitivity toward viscoelasticity remains unclear. In this study, we systematically exa...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Gong, Ze, Szczesny, Spencer E., Caliari, Steven R., Charrier, Elisabeth E., Chaudhuri, Ovijit, Cao, Xuan, Lin, Yuan, Mauck, Robert L., Janmey, Paul A., Burdick, Jason A., Shenoy, Vivek B.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2018
Teme:
PNAS Plus
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866566/
https://ncbi.nlm.nih.gov/pubmed/29507238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1716620115
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