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Opposite responses of normal hepatocytes and hepatocellular carcinoma cells to substrate viscoelasticity

The cellular microenvironment plays a critical role in cell differentiation, proliferation, migration, and homeostasis. Recent studies have shown the importance of substrate viscosity in determining cellular function. Here, we study the mechanoresponse of normal hepatocytes and hepatocellular carcin...

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Dettagli Bibliografici
Pubblicato in:Biomater Sci
Autori principali: Mandal, Kalpana, Gong, Ze, Rylander, Alexis, Shenoy, Vivek B., Janmey, Paul A
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8317444/
https://ncbi.nlm.nih.gov/pubmed/31903466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9bm01339c
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