Aptamer-Functionalized Drug Nanocarrier Improves Hepatocellular Carcinoma toward Normal by Targeting Neoplastic Hepatocytes

Site-specific delivery of chemotherapeutics specifically to neoplastic hepatocytes without affecting normal hepatocytes should be a focus for potential therapeutic management of hepatocellular carcinoma (HCC). The aptamer TLS 9a with phosphorothioate backbone modifications (L5) has not been explored...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Mol Ther Nucleic Acids
Главные авторы: Chakraborty, Samrat, Dlie, Zewdu Yilma, Chakraborty, Somdyuti, Roy, Somdatta, Mukherjee, Biswajit, Besra, Shila Elizabeth, Dewanjee, Saikat, Mukherjee, Alankar, Ojha, Probir Kumar, Kumar, Vinay, Sen, Ramkrishna
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Gene & Cell Therapy 2020
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7063179/
https://ncbi.nlm.nih.gov/pubmed/32146417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2020.01.034
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы