Matching material and cellular timescales maximizes cell spreading on viscoelastic substrates

Recent evidence has shown that, in addition to rigidity, the viscous response of the extracellular matrix (ECM) significantly affects the behavior and function of cells. However, the mechanism behind such mechanosensitivity toward viscoelasticity remains unclear. In this study, we systematically exa...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Gong, Ze, Szczesny, Spencer E., Caliari, Steven R., Charrier, Elisabeth E., Chaudhuri, Ovijit, Cao, Xuan, Lin, Yuan, Mauck, Robert L., Janmey, Paul A., Burdick, Jason A., Shenoy, Vivek B.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866566/
https://ncbi.nlm.nih.gov/pubmed/29507238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1716620115
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