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Stem Cell Differentiation is Regulated by Extracellular Matrix Mechanics
Stem cells mechanosense the stiffness of their microenvironment, which impacts differentiation. Although tissue hydration anti-correlates with stiffness, extracellular matrix (ECM) stiffness is clearly transduced into gene expression via adhesion and cytoskeleton proteins that tune fates. Cytoskelet...
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| Publicado no: | Physiology (Bethesda) |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5866410/ https://ncbi.nlm.nih.gov/pubmed/29212889 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiol.00026.2017 |
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