Tight coupling between nucleus and cell migration through the perinuclear actin cap

Por Kim, Dong-Hwee, Cho, Sangkyun, Wirtz, Denis
Publicado em 2014

Mechanosensing by the nucleus: From pathways to scaling relationships

Por Cho, Sangkyun, Irianto, Jerome, Discher, Dennis E.
Publicado no J Cell Biol (2017)

Mechanosensing of matrix by stem cells: from matrix heterogeneity, contractility, and the nucleus in pore-migration to cardiogenesis and muscle stem cells in vivo

Por Smith, Lucas, Cho, Sangkyun, Discher, Dennis E.
Publicado no Semin Cell Dev Biol (2017)

Stem Cell Differentiation is Regulated by Extracellular Matrix Mechanics

Por Smith, Lucas R., Cho, Sangkyun, Discher, Dennis E.
Publicado no Physiology (Bethesda) (2018)

MATRIX MECHANOSENSING: From Scaling Concepts in ’Omics Data to Mechanisms in the Nucleus, Regeneration, and Cancer

Por Discher, Dennis E., Smith, Lucas, Cho, Sangkyun, Colasurdo, Mark, García, Andrés J., Safran, Sam
Publicado no Annu Rev Biophys (2017)

Cross-linked matrix rigidity and soluble retinoids synergize in nuclear lamina regulation of stem cell differentiation

Por Ivanovska, Irena L., Swift, Joe, Spinler, Kyle, Dingal, Dave, Cho, Sangkyun, Discher, Dennis E.
Publicado no Mol Biol Cell (2017)

Progerin phosphorylation in interphase is lower and less mechanosensitive than lamin-A,C in iPS-derived mesenchymal stem cells

Por Cho, Sangkyun, Abbas, Amal, Irianto, Jerome, Ivanovska, Irena L., Xia, Yuntao, Tewari, Manu, Discher, Dennis E.
Publicado no Nucleus (2018)

Fractal heterogeneity in minimal matrix models of scars modulates stiff-niche stem-cell responses via the nuclear exit of a mechanorepressor

Por P. Dingal, P. C. Dave, Bradshaw, Andrew M., Cho, Sangkyun, Raab, Matthew, Buxboim, Amnon, Swift, Joe, Discher, Dennis E.
Publicado no Nat Mater (2015)

Matrix elasticity regulates lamin-A,C phosphorylation and turnover with feedback to actomyosin

Por Buxboim, Amnon, Swift, Joe, Irianto, Jerome, Spinler, Kyle R., Dingal, P. C. Dave P., Athirasala, Avathamsa, Kao, Yun-Ruei C., Cho, Sangkyun, Harada, Takamasa, Shin, Jae-Won, Discher, Dennis E.
Publicado no Curr Biol (2014)

SIRPA-Inhibited, Marrow-Derived Macrophages Engorge, Accumulate, and Differentiate in Antibody-Targeted Regression of Solid Tumors

Por Alvey, Cory M., Spinler, Kyle R., Irianto, Jerome, Pfeifer, Charlotte R., Hayes, Brandon, Xia, Yuntao, Cho, Sangkyun, Dingal, P.C.P. Dave, Hsu, Jake, Smith, Lucas, Tewari, Manu, Discher, Dennis E.
Publicado no Curr Biol (2017)

Mechanical signaling coordinates the embryonic heartbeat

Por Chiou, Kevin K., Rocks, Jason W., Chen, Christina Yingxian, Cho, Sangkyun, Merkus, Koen E., Rajaratnam, Anjali, Robison, Patrick, Tewari, Manorama, Vogel, Kenneth, Majkut, Stephanie F., Prosser, Benjamin L., Discher, Dennis E., Liu, Andrea J.
Publicado no Proc Natl Acad Sci U S A (2016)

Nuclear rupture at sites of high curvature compromises retention of DNA repair factors

Por Xia, Yuntao, Ivanovska, Irena L., Zhu, Kuangzheng, Smith, Lucas, Irianto, Jerome, Pfeifer, Charlotte R., Alvey, Cory M., Ji, Jiazheng, Liu, Dazhen, Cho, Sangkyun, Bennett, Rachel R., Liu, Andrea J., Greenberg, Roger A., Discher, Dennis E.
Publicado no J Cell Biol (2018)