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Mechanosensing of matrix by stem cells: from matrix heterogeneity, contractility, and the nucleus in pore-migration to cardiogenesis and muscle stem cells in vivo

Stem cells are particularly ‘plastic’ cell types that are induced by various cues to become specialized, tissuefunctional lineages by switching on the expression of specific gene programs. Matrix stiffness is among the cues that multiple stem cell types can sense and respond to. This seminar-style r...

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Bibliographische Detailangaben
Veröffentlicht in:Semin Cell Dev Biol
Hauptverfasser: Smith, Lucas, Cho, Sangkyun, Discher, Dennis E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5659905/
https://ncbi.nlm.nih.gov/pubmed/28587976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2017.05.025
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