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Mechanosensing by the nucleus: From pathways to scaling relationships

The nucleus is linked mechanically to the extracellular matrix via multiple polymers that transmit forces to the nuclear envelope and into the nuclear interior. Here, we review some of the emerging mechanisms of nuclear mechanosensing, which range from changes in protein conformation and transcripti...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Cho, Sangkyun, Irianto, Jerome, Discher, Dennis E.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5294790/
https://ncbi.nlm.nih.gov/pubmed/28043971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201610042
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