Therapeutic Manipulation of Ageing: Repurposing Old Dogs and Discovering New Tricks

Por Mallikarjun, Venkatesh, Swift, Joe
Publicado no EBioMedicine (2016)

The nuclear lamina is mechano-responsive to ECM elasticity in mature tissue

Por Swift, Joe, Discher, Dennis E.
Publicado em 2014

Roles of Cross-Membrane Transport and Signaling in the Maintenance of Cellular Homeostasis

Por Cho, Inchul, Jackson, Mark R., Swift, Joe
Publicado no Cell Mol Bioeng (2016)

Myosin-II inhibition and soft 2D matrix maximize multinucleation and cellular projections typical of platelet-producing megakaryocytes

Por Shin, Jae-Won, Swift, Joe, Spinler, Kyle R., Discher, Dennis E.
Publicado em 2011

Stem cell mechanobiology: diverse lessons from bone marrow

Por Ivanovska, Irena L., Shin, Jae-Won, Swift, Joe, Discher, Dennis E.
Publicado no Trends Cell Biol (2015)

Physical Plasticity of the Nucleus and its Manipulation

Por Ivanovska, Irena, Swift, Joe, Harada, Takamasa, Pajerowski, J. David, Discher, Dennis E.
Publicado em 2010

Optimal development of matrix elasticity

Por Majkut, Stephanie, Idema, Timon, Swift, Joe, Krieger, Christine, Liu, Andrea, Discher, Dennis E.
Publicado em 2013

Nuclear lamins in cancer

Por Irianto, Jerome, Pfeifer, Charlotte R., Ivanovska, Irena L., Swift, Joe, Discher, Dennis E.
Publicado no Cell Mol Bioeng (2016)

Cross-linked matrix rigidity and soluble retinoids synergize in nuclear lamina regulation of stem cell differentiation

Por Ivanovska, Irena L., Swift, Joe, Spinler, Kyle, Dingal, Dave, Cho, Sangkyun, Discher, Dennis E.
Publicado no Mol Biol Cell (2017)

Mechanobiology of bone marrow stem cells: from myosin-II forces to compliance of matrix and nucleus

Por Shin, Jae-Won, Swift, Joe, Ivanovska, Irena, Spinler, Kyle R., Buxboim, Amnon, Discher, Dennis E.
Publicado em 2013

Photoinitiated Destruction of Composite Porphyrin–Protein Polymersomes

Por Robbins, Gregory P., Jimbo, Masaya, Swift, Joe, Therien, Michael J., Hammer, Daniel A., Dmochowski, Ivan J.
Publicado em 2009

Lamins regulate cell trafficking and lineage maturation of adult human hematopoietic cells

Por Shin, Jae-Won, Spinler, Kyle R., Swift, Joe, Chasis, Joel A., Mohandas, Narla, Discher, Dennis E.
Publicado em 2013

Coordinated increase of nuclear tension and lamin-A with matrix stiffness outcompetes lamin-B receptor that favors soft tissue phenotypes

Por Buxboim, Amnon, Irianto, Jerome, Swift, Joe, Athirasala, Avathamsa, Shin, Jae-Won, Rehfeldt, Florian, Discher, Dennis E.
Publicado no Mol Biol Cell (2017)

Crawling from soft to stiff matrix polarizes the cytoskeleton and phosphoregulates myosin-II heavy chain

Por Raab, Matthew, Swift, Joe, P. Dingal, P.C. Dave, Shah, Palak, Shin, Jae-Won, Discher, Dennis E.
Publicado em 2012

Label-free mass spectrometry exploits dozens of detected peptides to quantify lamins in wildtype and knockdown cells

Por Swift, Joe, Harada, Takamasa, Buxboim, Amnon, Shin, Jae-Won, Tang, Hsin-Yao, Speicher, David W, Discher, Dennis E
Publicado em 2013

Fractal heterogeneity in minimal matrix models of scars modulates stiff-niche stem-cell responses via the nuclear exit of a mechanorepressor

Por P. Dingal, P. C. Dave, Bradshaw, Andrew M., Cho, Sangkyun, Raab, Matthew, Buxboim, Amnon, Swift, Joe, Discher, Dennis E.
Publicado no Nat Mater (2015)

Osmotic Challenge Drives Rapid and Reversible Chromatin Condensation in Chondrocytes

Por Irianto, Jerome, Swift, Joe, Martins, Rui P., McPhail, Graham D., Knight, Martin M., Discher, Dennis E., Lee, David A.
Publicado em 2013

Enhancing the Efficacy of Drug-loaded Nanocarriers against Brain Tumors by Targeted Radiation Therapy

Por Baumann, Brian C., Kao, Gary D., Mahmud, Abdullah, Harada, Takamasa, Swift, Joe, Chapman, Christina, Xu, Xiangsheng, Discher, Dennis E., Dorsey, Jay F.
Publicado em 2013

“Marker of Self” CD47 on lentiviral vectors decreases macrophage-mediated clearance and increases delivery to SIRPA-expressing lung carcinoma tumors

Por Sosale, Nisha G, Ivanovska, Irena I, Tsai, Richard K, Swift, Joe, Hsu, Jake W, Alvey, Cory M, Zoltick, Philip W, Discher, Dennis E
Publicado no Mol Ther Methods Clin Dev (2016)

Nuclear lamin stiffness is a barrier to 3D migration, but softness can limit survival

Por Harada, Takamasa, Swift, Joe, Irianto, Jerome, Shin, Jae-Won, Spinler, Kyle R., Athirasala, Avathamsa, Diegmiller, Rocky, Dingal, P.C. Dave P., Ivanovska, Irena L., Discher, Dennis E.
Publicado em 2014