Osmotic Challenge Drives Rapid and Reversible Chromatin Condensation in Chondrocytes

Changes in extracellular osmolality have been shown to alter gene expression patterns and metabolic activity of various cell types, including chondrocytes. However, mechanisms by which physiological or pathological changes in osmolality impact chondrocyte function remain unclear. Here we use quantit...

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Detalhes bibliográficos
Main Authors: Irianto, Jerome, Swift, Joe, Martins, Rui P., McPhail, Graham D., Knight, Martin M., Discher, Dennis E., Lee, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2013
Assuntos:
Cell Biophysics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3576538/
https://ncbi.nlm.nih.gov/pubmed/23442954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.01.006
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