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Nuclear lamin stiffness is a barrier to 3D migration, but softness can limit survival
Cell migration through solid tissue often involves large contortions of the nucleus, but biological significance is largely unclear. The nucleoskeletal protein lamin-A varies both within and between cell types and was shown here to contribute to cell sorting and survival in migration through constra...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
The Rockefeller University Press
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3941057/ https://ncbi.nlm.nih.gov/pubmed/24567359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201308029 |
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