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Mechanism of regulation of stem cell differentiation by matrix stiffness

Stem cell behaviors are regulated by multiple microenvironmental cues. As an external signal, mechanical stiffness of the extracellular matrix is capable of governing stem cell fate determination, but how this biophysical cue is translated into intracellular signaling remains elusive. Here, we eluci...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Lv, Hongwei, Li, Lisha, Sun, Meiyu, Zhang, Yin, Chen, Li, Rong, Yue, Li, Yulin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445995/
https://ncbi.nlm.nih.gov/pubmed/26012510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-015-0083-4
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