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Mechanism of regulation of stem cell differentiation by matrix stiffness

Stem cell behaviors are regulated by multiple microenvironmental cues. As an external signal, mechanical stiffness of the extracellular matrix is capable of governing stem cell fate determination, but how this biophysical cue is translated into intracellular signaling remains elusive. Here, we eluci...

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Podrobná bibliografie
Vydáno v:Stem Cell Res Ther
Hlavní autoři: Lv, Hongwei, Li, Lisha, Sun, Meiyu, Zhang, Yin, Chen, Li, Rong, Yue, Li, Yulin
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445995/
https://ncbi.nlm.nih.gov/pubmed/26012510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-015-0083-4
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