Extracellular matrix stiffness controls osteogenic differentiation of mesenchymal stem cells mediated by integrin α5

BACKGROUND: Human mesenchymal stem cell (hMSC) differentiation into osteoblasts has important clinical significance in treating bone injury, and the stiffness of the extracellular matrix (ECM) has been shown to be an important regulatory factor for hMSC differentiation. The aim of this study was to...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Sun, Meiyu, Chi, Guangfan, Xu, Juanjuan, Tan, Ye, Xu, Jiayi, Lv, Shuang, Xu, Ziran, Xia, Yuhan, Li, Lisha, Li, Yulin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5831741/
https://ncbi.nlm.nih.gov/pubmed/29490668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-018-0798-0
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