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Extracellular matrix stiffness controls osteogenic differentiation of mesenchymal stem cells mediated by integrin α5

BACKGROUND: Human mesenchymal stem cell (hMSC) differentiation into osteoblasts has important clinical significance in treating bone injury, and the stiffness of the extracellular matrix (ECM) has been shown to be an important regulatory factor for hMSC differentiation. The aim of this study was to...

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Bibliographische Detailangaben
Veröffentlicht in:Stem Cell Res Ther
Hauptverfasser: Sun, Meiyu, Chi, Guangfan, Xu, Juanjuan, Tan, Ye, Xu, Jiayi, Lv, Shuang, Xu, Ziran, Xia, Yuhan, Li, Lisha, Li, Yulin
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5831741/
https://ncbi.nlm.nih.gov/pubmed/29490668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-018-0798-0
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