Extracellular matrix stiffness controls osteogenic differentiation of mesenchymal stem cells mediated by integrin α5

BACKGROUND: Human mesenchymal stem cell (hMSC) differentiation into osteoblasts has important clinical significance in treating bone injury, and the stiffness of the extracellular matrix (ECM) has been shown to be an important regulatory factor for hMSC differentiation. The aim of this study was to...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Stem Cell Res Ther
Main Authors: Sun, Meiyu, Chi, Guangfan, Xu, Juanjuan, Tan, Ye, Xu, Jiayi, Lv, Shuang, Xu, Ziran, Xia, Yuhan, Li, Lisha, Li, Yulin
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5831741/
https://ncbi.nlm.nih.gov/pubmed/29490668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-018-0798-0
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