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Mechanism of regulation of stem cell differentiation by matrix stiffness

Stem cell behaviors are regulated by multiple microenvironmental cues. As an external signal, mechanical stiffness of the extracellular matrix is capable of governing stem cell fate determination, but how this biophysical cue is translated into intracellular signaling remains elusive. Here, we eluci...

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Publicat a:Stem Cell Res Ther
Autors principals: Lv, Hongwei, Li, Lisha, Sun, Meiyu, Zhang, Yin, Chen, Li, Rong, Yue, Li, Yulin
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445995/
https://ncbi.nlm.nih.gov/pubmed/26012510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-015-0083-4
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