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Manipulating the mechanics of extracellular matrix to study effects on the nucleus and its structure

Tissues such as brain, muscle, and bone differ greatly not only in their biological functions but also in their mechanical properties. Stiffness of the extracellular microenvironment affects processes such as cell polarization and DNA replication, thereby regulating nuclear size, shape, and levels o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Methods
Hauptverfasser: Xia, Yuntao, Cho, Sangkyun, Vashisth, Manasvita, Ivanovska, Irena L., Dingal, P. C. Dave P., Discher, Dennis E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6508970/
https://ncbi.nlm.nih.gov/pubmed/30593865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2018.12.009
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