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Manipulating the mechanics of extracellular matrix to study effects on the nucleus and its structure

Tissues such as brain, muscle, and bone differ greatly not only in their biological functions but also in their mechanical properties. Stiffness of the extracellular microenvironment affects processes such as cell polarization and DNA replication, thereby regulating nuclear size, shape, and levels o...

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Bibliografische gegevens
Gepubliceerd in:Methods
Hoofdauteurs: Xia, Yuntao, Cho, Sangkyun, Vashisth, Manasvita, Ivanovska, Irena L., Dingal, P. C. Dave P., Discher, Dennis E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6508970/
https://ncbi.nlm.nih.gov/pubmed/30593865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2018.12.009
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