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In vivo magnetofection: a novel approach for targeted topical delivery of nucleic acids for rectoanal motility disorders

In these studies, we developed a novel approach of in vivo magnetofection for localized delivery of nucleic acids such as micro-RNA-139-5p (miR-139-5p; which is known to target Rho kinase2) to the circular smooth muscle layer of the internal anal sphincter (IAS). The IAS tone is known to play a majo...

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Bibliografski detalji
Izdano u:Am J Physiol Gastrointest Liver Physiol
Glavni autori: Singh, Jagmohan, Mohanty, Ipsita, Rattan, Satish
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866375/
https://ncbi.nlm.nih.gov/pubmed/29051187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00233.2017
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