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BDNF augments rat internal anal sphincter smooth muscle tone via RhoA/ROCK signaling and nonadrenergic noncholinergic relaxation via increased NO release

Presently, there are no studies examining the neuromodulatory effects of brain-derived neurotropic factor (BDNF) on the basal internal anal sphincter (IAS) tone and nonadrenergic noncholinergic (NANC) relaxation. To examine this, we determined the neuromuscular effects of BDNF on basal IAS smooth mu...

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Vydáno v:Am J Physiol Gastrointest Liver Physiol
Hlavní autoři: Singh, Arjun, Mohanty, Ipsita, Singh, Jagmohan, Rattan, Satish
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6985850/
https://ncbi.nlm.nih.gov/pubmed/31682160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00247.2019
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