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BDNF rescues aging-associated internal anal sphincter dysfunction

Aging can lead to rectoanal incontinence due to internal anal sphincter (IAS) dysfunction, which is characterized by a decrease in IAS tone and contractility and an increase in nonadrenergic noncholinergic (NANC) relaxation. We aimed to determine whether brain-derived neurotropic factor (BDNF) rescu...

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Vydáno v:Am J Physiol Gastrointest Liver Physiol
Hlavní autoři: Singh, Arjun, Rattan, Satish
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8321795/
https://ncbi.nlm.nih.gov/pubmed/34075793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00090.2021
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