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Nature of extracellular signal that triggers RhoA/ROCK activation for the basal internal anal sphincter tone in humans
The extracellular signal that triggers activation of rho-associated kinase (RhoA/ROCK), the major molecular determinant of basal internal anal sphincter (IAS) smooth muscle tone, is not known. Using human IAS tissues, we identified the presence of the biosynthetic machineries for angiotensin II (ANG...
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| Publicado no: | Am J Physiol Gastrointest Liver Physiol |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4451323/ https://ncbi.nlm.nih.gov/pubmed/25882611 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00017.2015 |
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