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COX-1 vs. COX-2 as a determinant of basal tone in the internal anal sphincter

Prostanoids, produced endogenously via cyclooxygenases (COXs), have been implicated in the sustained contraction of different smooth muscles. The two major types of COXs are COX-1 and COX-2. The COX subtype involved in the basal state of the internal anal sphincter (IAS) smooth muscle tone is not kn...

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Detalhes bibliográficos
Main Authors: de Godoy, Márcio A. F., Rattan, Neeru, Rattan, Satish
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643912/
https://ncbi.nlm.nih.gov/pubmed/19056763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.90485.2008
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