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Nature of extracellular signal that triggers RhoA/ROCK activation for the basal internal anal sphincter tone in humans

The extracellular signal that triggers activation of rho-associated kinase (RhoA/ROCK), the major molecular determinant of basal internal anal sphincter (IAS) smooth muscle tone, is not known. Using human IAS tissues, we identified the presence of the biosynthetic machineries for angiotensin II (ANG...

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書誌詳細
出版年:Am J Physiol Gastrointest Liver Physiol
主要な著者: Rattan, Satish, Singh, Jagmohan, Kumar, Sumit, Phillips, Benjamin
フォーマット: Artigo
言語:Inglês
出版事項: American Physiological Society 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4451323/
https://ncbi.nlm.nih.gov/pubmed/25882611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00017.2015
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