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Nature of extracellular signal that triggers RhoA/ROCK activation for the basal internal anal sphincter tone in humans

The extracellular signal that triggers activation of rho-associated kinase (RhoA/ROCK), the major molecular determinant of basal internal anal sphincter (IAS) smooth muscle tone, is not known. Using human IAS tissues, we identified the presence of the biosynthetic machineries for angiotensin II (ANG...

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Detaylı Bibliyografya
Yayımlandı:Am J Physiol Gastrointest Liver Physiol
Asıl Yazarlar: Rattan, Satish, Singh, Jagmohan, Kumar, Sumit, Phillips, Benjamin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4451323/
https://ncbi.nlm.nih.gov/pubmed/25882611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00017.2015
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