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In vivo magnetofection: a novel approach for targeted topical delivery of nucleic acids for rectoanal motility disorders
In these studies, we developed a novel approach of in vivo magnetofection for localized delivery of nucleic acids such as micro-RNA-139-5p (miR-139-5p; which is known to target Rho kinase2) to the circular smooth muscle layer of the internal anal sphincter (IAS). The IAS tone is known to play a majo...
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| Publicado no: | Am J Physiol Gastrointest Liver Physiol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5866375/ https://ncbi.nlm.nih.gov/pubmed/29051187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00233.2017 |
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