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In vivo magnetofection: a novel approach for targeted topical delivery of nucleic acids for rectoanal motility disorders
In these studies, we developed a novel approach of in vivo magnetofection for localized delivery of nucleic acids such as micro-RNA-139-5p (miR-139-5p; which is known to target Rho kinase2) to the circular smooth muscle layer of the internal anal sphincter (IAS). The IAS tone is known to play a majo...
Enregistré dans:
| Publié dans: | Am J Physiol Gastrointest Liver Physiol |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Physiological Society
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5866375/ https://ncbi.nlm.nih.gov/pubmed/29051187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00233.2017 |
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