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Bioengineered human IAS reconstructs with functional and molecular properties similar to intact IAS

Because of its critical importance in rectoanal incontinence, we determined the feasibility to reconstruct internal anal sphincter (IAS) from human IAS smooth muscle cells (SMCs) with functional and molecular attributes similar to the intact sphincter. The reconstructs were developed using SMCs from...

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Autors principals: Singh, Jagmohan, Rattan, Satish
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468534/
https://ncbi.nlm.nih.gov/pubmed/22790596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00112.2012
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