Endogenous LINE-1 reverse transcriptase activity in platelets controls translational events through RNA-DNA hybrids

OBJECTIVE: One source of endogenous reverse transcriptase (eRT) activity in nucleated cells is the Long Interspersed Element-1 (LINE-1/L1), a non-LTR retrotransposon that is implicated in the regulation of gene expression. Nevertheless, the presence and function of eRT activity and LINE-1 in human p...

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Bibliografiske detaljer
Udgivet i:Arterioscler Thromb Vasc Biol
Main Authors: Schwertz, Hansjörg, Rowley, Jesse W., Schumann, Gerald G., Thorack, Ulrike, Campbell, Robert A., Manne, Bhanu Kanth, Zimmerman, Guy A., Weyrich, Andrew S., Rondina, Matthew T.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5864535/
https://ncbi.nlm.nih.gov/pubmed/29301786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.117.310552
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