Sepsis alters the transcriptional and translational landscape of human and murine platelets

There is increasing recognition that platelets have a functional role in the pathophysiology of sepsis, though this role has not been precisely defined. Whether sepsis alters the human platelet transcriptome and translational landscape has never been established. We used parallel techniques of RNA s...

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Publicado en:Blood
Autores principales: Middleton, Elizabeth A., Rowley, Jesse W., Campbell, Robert A., Grissom, Colin K., Brown, Samuel M., Beesley, Sarah J., Schwertz, Hansjörg, Kosaka, Yasuhiro, Manne, Bhanu K., Krauel, Krystin, Tolley, Neal D., Eustes, Alicia S., Guo, Li, Paine, Robert, Harris, Estelle S., Zimmerman, Guy A., Weyrich, Andrew S., Rondina, Matthew T.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2019
Materias:
Plenary Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6753624/
https://ncbi.nlm.nih.gov/pubmed/31366617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019000067
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