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Phospho-inositide-dependent kinase 1 regulates signal dependent translation in megakaryocytes and platelets

BACKGROUND: Regulated protein synthesis is essential for megakaryocyte (MK) and platelet functions, including platelet production and activation. PDK1 (phospho-inositide-dependent kinase 1) regulates platelet functional responses and has been associated with circulating platelet counts. Whether PDK1...

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Detalhes bibliográficos
Publicado no:J Thromb Haemost
Main Authors: Manne, Bhanu Kanth, Bhatlekar, Seema, Middleton, Elizabeth A., Weyrich, Andrew S., Borst, Oliver, Rondina, Matthew T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7192796/
https://ncbi.nlm.nih.gov/pubmed/31997536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.14748
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