Učitavanje...
Mcl-1 and Bcl-x(L) sequestration of Bak confers differential resistance to BH3-only proteins
The prosurvival Bcl-2 family proteins Mcl-1 and Bcl-x(L) inhibit apoptosis by sequestering BH3-only proteins such as Bid and Bim (MODE 1) or the effector proteins Bak and Bax (MODE 2). To better understand the contributions of MODE 1 and MODE 2 in blocking cell death, and thus how to bypass resistan...
Spremljeno u:
| Izdano u: | Cell Death Differ |
|---|---|
| Glavni autori: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group UK
2018
|
| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5864222/ https://ncbi.nlm.nih.gov/pubmed/29459767 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-017-0010-6 |
| Oznake: |
Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!
|