Transplanted Senescent Cells Induce an Osteoarthritis-Like Condition in Mice

Osteoarthritis (OA) is the leading form of arthritis in the elderly, causing pain, disability, and immobility. OA has been associated with accumulation of senescent cells in or near joints. However, evidence for a causal link between OA and cellular senescence is lacking. Here, we present a novel se...

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Detaylı Bibliyografya
Yayımlandı:J Gerontol A Biol Sci Med Sci
Asıl Yazarlar: Xu, Ming, Bradley, Elizabeth W., Weivoda, Megan M., Hwang, Soyun M., Pirtskhalava, Tamar, Decklever, Teresa, Curran, Geoffry L., Ogrodnik, Mikolaj, Jurk, Diana, Johnson, Kurt O., Lowe, Val, Tchkonia, Tamar, Westendorf, Jennifer J., Kirkland, James L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2017
Konular:
Brief Report
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5861939/
https://ncbi.nlm.nih.gov/pubmed/27516624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glw154
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