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Dissection of the Role of VIMP in Endoplasmic Reticulum-Associated Degradation of CFTRΔF508
Endoplasmic reticulum (ER)-associated protein degradation (ERAD) is an important quality control mechanism that eliminates misfolded proteins from the ER. The Derlin-1/VCP/VIMP protein complex plays an essential role in ERAD. Although the roles of Derlin-1 and VCP are relatively clear, the functiona...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5859151/ https://ncbi.nlm.nih.gov/pubmed/29555962 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23284-8 |
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