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Syntaxin 8 and the Endoplasmic Reticulum Processing of ΔF508-CFTR
BACKGROUND/AIMS: Cystic fibrosis (CF) is a lethal recessive disorder caused by mutations in the CF transmembrane conductance regulator (CFTR). ΔF508, the most common mutation, is a misfolded protein that is retained in the endoplasmic reticulum and degraded, precluding delivery to the cell surface [...
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| Publicat a: | Cell Physiol Biochem |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6482459/ https://ncbi.nlm.nih.gov/pubmed/30485852 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000495596 |
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