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Syntaxin 8 and the Endoplasmic Reticulum Processing of ΔF508-CFTR

BACKGROUND/AIMS: Cystic fibrosis (CF) is a lethal recessive disorder caused by mutations in the CF transmembrane conductance regulator (CFTR). ΔF508, the most common mutation, is a misfolded protein that is retained in the endoplasmic reticulum and degraded, precluding delivery to the cell surface [...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cell Physiol Biochem
Päätekijät: Sabirzhanova, Inna, Boinot, Clément, Guggino, William B., Cebotaru, Liudmila
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6482459/
https://ncbi.nlm.nih.gov/pubmed/30485852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000495596
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