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Small Heat-Shock Proteins Select ΔF508-CFTR for Endoplasmic Reticulum-associated Degradation

Secreted proteins that fail to achieve their native conformations, such as cystic fibrosis transmembrane conductance regulator (CFTR) and particularly the ΔF508-CFTR variant can be selected for endoplasmic reticulum (ER)-associated degradation (ERAD) by molecular chaperones. Because the message corr...

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Библиографические подробности
Главные авторы: Ahner, Annette, Nakatsukasa, Kunio, Zhang, Hui, Frizzell, Raymond A., Brodsky, Jeffrey L.
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Cell Biology 2007
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1805084/
https://ncbi.nlm.nih.gov/pubmed/17182856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-05-0458
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