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Dissection of the Role of VIMP in Endoplasmic Reticulum-Associated Degradation of CFTRΔF508
Endoplasmic reticulum (ER)-associated protein degradation (ERAD) is an important quality control mechanism that eliminates misfolded proteins from the ER. The Derlin-1/VCP/VIMP protein complex plays an essential role in ERAD. Although the roles of Derlin-1 and VCP are relatively clear, the functiona...
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| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5859151/ https://ncbi.nlm.nih.gov/pubmed/29555962 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23284-8 |
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