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Investigation of Amide Bond Formation during Dehydrophos Biosynthesis
Dehydrophos is a tripeptide phosphonate antibiotic produced by Streptomyces luridus. Its biosynthetic pathway involves the use of aminoacyl-tRNA (aa-tRNA) for amide bond formation. The first amide bond during biosynthesis is formed by DhpH-C, a peptidyltransferase that utilizes Leu-tRNA(Leu). DhpH-C...
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| Udgivet i: | ACS Chem Biol |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5856630/ https://ncbi.nlm.nih.gov/pubmed/29303545 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.7b00949 |
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