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Structure–activity relationships of the phosphonate antibiotic dehydrophos

Synthetic derivatives of the phosphonate antibiotic dehydrophos were tested for antimicrobial activity. Both the phosphonate monomethyl ester and the vinyl phosphonate moiety proved to be important for bacteriocidal activity of the natural product.

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Detalhes bibliográficos
Main Authors: Kuemin, Michael, van der Donk, Wilfred A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109733/
https://ncbi.nlm.nih.gov/pubmed/20871915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c0cc02958k
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