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Structure–activity relationships of the phosphonate antibiotic dehydrophos

Synthetic derivatives of the phosphonate antibiotic dehydrophos were tested for antimicrobial activity. Both the phosphonate monomethyl ester and the vinyl phosphonate moiety proved to be important for bacteriocidal activity of the natural product.

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Autores principales: Kuemin, Michael, van der Donk, Wilfred A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109733/
https://ncbi.nlm.nih.gov/pubmed/20871915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c0cc02958k
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