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Structure–activity relationships of the phosphonate antibiotic dehydrophos

Synthetic derivatives of the phosphonate antibiotic dehydrophos were tested for antimicrobial activity. Both the phosphonate monomethyl ester and the vinyl phosphonate moiety proved to be important for bacteriocidal activity of the natural product.

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Autors principals: Kuemin, Michael, van der Donk, Wilfred A.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109733/
https://ncbi.nlm.nih.gov/pubmed/20871915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c0cc02958k
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