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Structure–activity relationships of the phosphonate antibiotic dehydrophos

Synthetic derivatives of the phosphonate antibiotic dehydrophos were tested for antimicrobial activity. Both the phosphonate monomethyl ester and the vinyl phosphonate moiety proved to be important for bacteriocidal activity of the natural product.

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Détails bibliographiques
Auteurs principaux: Kuemin, Michael, van der Donk, Wilfred A.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109733/
https://ncbi.nlm.nih.gov/pubmed/20871915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c0cc02958k
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