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ATR/CHK1 inhibitors and cancer therapy
The cell cycle checkpoint proteins ataxia-telangiectasia-mutated-and-Rad3-related kinase (ATR) and its major downstream effector checkpoint kinase 1 (CHK1) prevent the entry of cells with damaged or incompletely replicated DNA into mitosis when the cells are challenged by DNA damaging agents, such a...
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| Published in: | Radiother Oncol |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5856582/ https://ncbi.nlm.nih.gov/pubmed/29054375 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.radonc.2017.09.043 |
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